How Long Does Wegovy Stay in Your System?

Introduction
Wegovy (Semaglutide) is a medication used for weight loss, but understanding its pharmacokinetics—specifically how long it stays in your system—can be important for managing side effects, planning discontinuation, or switching medications.

Pharmacokinetics of Wegovy

  • Half-Life: The half-life of Wegovy is approximately 7 days.
  • Full Elimination: It typically takes about 5 half-lives for a drug to be cleared from the system, so Wegovy will generally be fully eliminated in about 5 weeks after the last dose.

Factors Influencing Elimination

  • Dosage and Duration of Use: Longer use or higher doses may prolong the presence of the drug in your system.
  • Renal Function: Impaired kidney function may slow down the elimination process.
ParameterDetails
Half-Life7 days
Full Clearance~5 weeks after last dose
Impact of Renal FunctionDelays elimination

Conclusion
Wegovy stays in your system for approximately 5 weeks after the last dose. Understanding this timeline can help in planning medication adjustments or addressing any side effects.

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