Introduction:

Januvia and Tradjenta are both DPP-4 inhibitors, which means they help control blood sugar in people with Type 2 diabetes. Let’s look at how they are different and which one might be best for you.

Mechanism of Action:

•             How Januvia works: Januvia helps increase the amount of insulin your body releases after you eat. It also stops your liver from making too much sugar.

•             How Tradjenta works: Tradjenta works in the same way, but it may last longer in your body.

Efficacy:

•             A1c reduction: Both Januvia and Tradjenta help lower A1c levels. There’s not a huge difference between the two in how well they work.

•             Weight impact: Neither Januvia nor Tradjenta are known for helping with weight loss, but they don’t usually cause weight gain either.

Side Effects:

•             Common side effects: Both drugs can cause mild side effects, like cold symptoms and joint pain.

•             Serious risks: In rare cases, both can cause serious side effects like pancreatitis or allergic reactions.

Cost and Coverage:

•             Pricing: Januvia and Tradjenta can be expensive, but they are covered by most insurance plans. It’s worth inquiring if your local pharmacy has the generic of Tradjenta, linagliptin. This may cost considerably less.

•             Patient assistance programs: Patient assistance programs are often available for brand name drugs like these that offer significant clinical benefit for chronic conditions.

Conclusion:

Januvia and Tradjenta are very similar. If you need a medicine that helps lower blood sugar without causing weight gain, either might work for you. Though I would typically recommend a GLP1ra or an SGLT2 drug, talk to your doctor to find out which is best for your needs.