Semaglutide vs. Tirzepatide: Mechanisms, Differences, & Outcomes

Overview

Semaglutide and tirzepatide are two medicines that help with weight loss. They use your body’s natural hunger hormones.

How They Work

•             Semaglutide: Works primarily with GLP 1 to help you feel full and lower blood sugar.

•             Tirzepatide: Acts on both GLP 1 and GIP, which some people lose more weight.

Side Effects & Considerations

•             Mild Side Effects: Both can cause minor upset stomach or nausea that usually fades.

•             Doctor’s Guidance: Your doctor will look at your health history and body response to decide the best option, though, for most individuals, if you are a candidate for one, you’re likely a candidate for the other.

Choosing the Right Medicine

Discuss with your healthcare provider to learn more about the benefits and any potential risks. Give your medical insurance a call as well to see if your employer covers the injections.

In Short

Both semaglutide and tirzepatide help control hunger and blood sugar. The key difference is that tirzepatide works on two hormones, which leads to some meaningful differences in weight loss outcomes (tirzepatide helps lose more). Talk with your doctor to find the best fit for your weight loss journey.