Switching from Semaglutide to Tirzepatide Dose Conversion Best Practices

Overview

Sometimes switching from semaglutide to tirzepatide is needed. Since tirzepatide works on two hormones, the dose must be adjusted carefully.

The Switching Process

  • Stop semaglutide: the washout period is about 1-2 weeks.
  • Gradual Increase of tirzepatide: Slowly raise the dose accordingly with the dose taper
  • Monitoring: Your healthcare team will monitor the primary monitoring objectives, like weight loss or HbA1c level

Why It’s Important

    • Safety First: A careful conversion minimizes side effects. However, the side effects will typically be the same as those on semaglutide
    • Effective Transition: A smooth switch ensures you continue to lose weight safely or managed your type 2 diabetes well.

In Short

Switching from semaglutide to tirzepatide requires a careful dose conversion. Follow your healthcare team’s instructions and ask questions to ensure a safe and effective transition.